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Publication Abstract Display
Type: Published Abstract
Title: Methamphetamine-associated psychosis: A model for biomarker discovery in schizophrenia.
Authors: Bousman C
Year: 2010
Publication: Trends in Psychiatric Genetics Meeting
Volume: Issue: Pages:
Abstract:Methamphetamine-associated psychosis (MAP) has been considered a pharmacological or environmental pathogen model of schizophrenia (SCZ) due in part to similarities in clinical presentation (i.e. paranoia, hallucinations, disorganized speech, and negative symptoms), response to treatment (e.g. neuroleptics), and pathologic mechanisms (e.g. central dopaminergic neurotransmission) of both conditions. In this presentation, I will provide an introduction to the typical clinical features and course of MAP as well as a review and discussion of the current putative genetic, neurocognitive, and imaging markers for MAP. The presentation will conclude with a discussion of the future directions and application of the MAP model with specific focus on how it may serve to elucidate further the complex neuromechanisms and discovery of viable biomarkers of SCZ.

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