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Publication Abstract Display
Type: Poster
Title: Mitochondrial injury and cognitive function in HIV infection and methamphetamine use.
Authors: Var S
Date: 02-23-2015
Abstract:When comparing brain samples from four brain regions, levels of mtDNA and mitochondrial injury were highest in the white matter of the middle frontal gyrus ( Figure 2 ) . Higher abundance of the common deletion was associated with increasing age ( Figure 3 ) . MtDNA damage was also associated with better neurocognitive function only in METH users ( Table 2 ) . METH use appears to have a protective effect on mitochondrial injury . METH use has been shown to increase autophagy and mediate neuroprotection at low doses .

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