Publication Abstract Display
Type: Published Manuscript
Title: Variable Delta-9-Tetrahydrocannabinol Pharmacokinetics And Pharmacodynamics After Cannabis Smoking in Regular Users.
Authors: Liyanage M, Nikanjam M, Capparelli EV, Suhandynata RT, Fitzgerald RL, Marcotte TD, Grant I, Momper JD
Year: 2023
Publication: Therapeutic Drug Monitoring
Volume: 45 Issue: 5 Pages: 689-696
Abstract:Despite its federally restricted status, cannabis is widely used medicinally and recreationally. The pharmacokinetics (PK) and central nervous system (CNS) effects of tetrahydrocannabinol (THC), the major psychoactive cannabinoid, are not well understood. The objective of this study was to develop a population PK model of inhaled THC, including sources of variability, and to conduct an exploratory analysis of potential exposure-response relationships.

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