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Publication Abstract Display |
Type: Poster |
Title: Persistent HIV in the central nervous system (CNS) during treatment is associated with worse antiretroviral therapy (ART) penetration and cognitive impairment. |
Authors: Letendre S, McClernon D, Ellis RJ, Munoz-Moreno J, Way L, Clifford D, Collier A, Gelman B, Marra C, McArthur J, McCutchan A, Morgello S, Simpson D, Franklin D, Heaton R, Grant I, and the CHARTER Group |
Date: 02-08-2009 |
Abstract:"Background: Cognitive impairment can occur or persist during ART. Explanations include co-morbidities, neurotoxic ART, persistent neuroinflammation, or persistent HIV replication. This analysis assessed whether low levels of HIV in CSF were associated with inter-individual differences in ART and neuropsychological (NP) performance. |