| Publication Abstract Display |
| Type: Published Manuscript |
| Title: Performances on the CogState and Standard Neuropsychological Batteries among HIV patients without dementia. |
| Authors: Overton ET, Kauwe JSK, Paul R, Tashima K, Tate DF, Patel P, Carpenter CCJ, Patty D, Brooks JT, Clifford DB |
| Year: 2011 |
| Publication: AIDS and Behavior |
| Volume: 15 Issue: 8 Pages: 1902-1909 |
| Abstract:HIV-associated neurocognitive disorders remain prevalent but challenging to diagnose particularly among non-demented individuals. To determine whether a brief computerized battery correlates with formal neurocognitive testing, we identified 46 HIV-infected persons who had undergone both formal neurocognitive testing and a brief computerized battery. Simple detection tests correlated best with formal neuropsychological testing. By multivariable regression model, 53% of the variance in the composite Global Deficit Score was accounted for by elements from the brief computerized tool (P < 0.01). These data confirm previous correlation data with the computerized battery. Using the five significant parameters from the regression model in a Receiver Operating Characteristic curve, 90% of persons were accurately classified as being cognitively impaired or not. The test battery requires additional evaluation, specifically for identifying persons with mild impairment, a state upon which interventions may be effective. |