| Publication Abstract Display | | Type: Poster | | Title: Persisting High Prevalence of HIV Distal Sensory Peripheral Neuropathy (DSPN) in the Era of Combination Antiretroviral Therapy (CART): Correlates in the CHARTER Study. | | Authors: Ellis R, Rosario D, Clifford D, McArthur J, Simpson D, Alexander T, Gelman B, Grant I | | Date: 02-08-2009 | | Abstract:Before combination antiretroviral therapy (CART) was introduced, neuropathic pain
due to Distal Sensory Polyneuropathy (DSPN) was the most prevalent neurologic
complaint in HIV.
• DSPN symptoms include hyperalgesia, tingling, numbness, and pain.
• CART has resulted in substantial immune reconstitution among the HIV population.
• D-drugs, know to be associated with the onset of neuropathic pain, have also
declined in use.
• Due to an aging HIV population, current estimates of both DSPN and pain
prevalences, associated risk factors and overall impact are necessary for effective
therapeutic innovations. |
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