Publication Abstract Display
Type: Published Abstract
Title: Cognitive impairment predicts functional declines in Hepatitis C infection.
Authors: Vigil O, Posada C, Woods SP, Atkinson JH, Heaton RK, Perry W, Hassanein TI, Grant I, Letendre SL, and the HNRC Group
Year: 2007
Publication: The Clinical Neuropsychologist
Volume: 21 Issue: 4 Pages: 702
Abstract:Research increasingly supports the neurovirulence of chronic infection with the hepatitis C virus (HCV). HCV infection has been associated with neuropsychological impairment and declines in daily functioning. This study examined whether HCV- associated neuropsychological impairment is predictive of functional declines. In 106 volunteers with HCV infection, self-reported functional declines correlated significantly with impairment in processing speed and motor functioning, independent of depression and HCV disease variables. These findings suggest that consideration of cognitive functioning, as well as affective and physical factors, are important in the clinical evaluation and treatment of individuals living with HCV infection.

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