Publication Abstract Display | Type: Published Abstract | Title: Cognitive impairment predicts functional declines in Hepatitis C infection. | Authors: Vigil O, Posada C, Woods SP, Atkinson JH, Heaton RK, Perry W, Hassanein TI, Grant I, Letendre SL, and the HNRC Group | Year: 2007 | Publication: The Clinical Neuropsychologist | Volume: 21 Issue: 4 Pages: 702 | Abstract:Research increasingly supports the neurovirulence of chronic infection with
the hepatitis C virus (HCV). HCV infection has been associated with neuropsychological
impairment and declines in daily functioning. This study examined
whether HCV- associated neuropsychological impairment is predictive of functional
declines. In 106 volunteers with HCV infection, self-reported functional declines correlated
significantly with impairment in processing speed and motor functioning, independent
of depression and HCV disease variables. These findings suggest that
consideration of cognitive functioning, as well as affective and physical factors, are important
in the clinical evaluation and treatment of individuals living with HCV infection. |
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