Publication Abstract Display | Type: Poster | Title: Habitual prospective memory in HIV infection. | Authors: Woods SP, Weber E, Cattie JE, Cushman C, Grant I, and the HNRP Group | Date: 02-15-2012 | Abstract:The prevalence of older adults living with HIV infection is on the rise, due in large
part to the success of antiretroviral therapies. Older age and HIV infection may
confer additive adverse effects on neurocognitive outcomes, including
prospective memory (PM), which may increase the risk of everyday functioning
complications. To extend this literature, the current study evaluated the combined
effects of HIV and aging on habitual PM, which is hypothesized to better reflect
real-world situations in which an intention recurs at regular intervals (e.g.,
medication adherence). Participants included 55 older (i.e., >50 years) HIV+ and
41 older HIV- subjects, as well as 34 younger (i.e., < 40 years) HIV+ and 39
younger HIV- participants. Subjects completed a habitual PM task in which they
were instructed to press the space bar one time per one-minute trial of a
computerized Stroop paradigm (but not within the first 10 seconds). Results
showed main effects of HIV serostatus (p=.04), such that HIV-infected subjects
had higher rates of omission errors (d=.33), but no main effect of age or
interaction (ps>.10). No main effects or interactions were observed for early
responding or errors of commission (ps>.10). Within the HIV+ groups, higher
rates of habitual PM omission errors correlated with executive dysfunction,
retrospective memory deficits, and semi-naturalistic PM failures (ps<.05).
Independent of age, persons living with HIV infection may experience difficulty
fulfilling future intentions, even when such intentions recur at regular intervals.
The possible unique role of HIV-associated habitual PM deficits in everyday
functioning outcomes may warrant investigation. |
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