| Publication Abstract Display | | Type: Poster | | Title: Recent cannabis use in HIV infection is associated with reduced IL-16 in CSF. | | Authors: Ellis R, Li Y, Peterson S, Schrier R, South E, Iudicello J, Letendre S, Morgan EE, Cherner M, Grant I | | Date: 04-10-2018 | | Abstract:Conclusions and Limitations
CSF IL-16 lower with recent cannabis use, but not quantity or density of use
Lower CSF IL-16 may reflect reduced microglial activation related to cannabinoids
Cannabis - IL-16 association present in CSF but not blood
compartmentalization of immune responses?
Greater concentration of cannabinoids in CNS due to lipophilicity?
CSF IL-16 levels higher in men than women - sex differences in neuroinflammation?
Limitations
Small pilot study; selection bias; omitted variable bias
Can't distinguish cannabidiol vs. THC; no THC/CBD levels
Smoking vs. vaping. |
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