Publication Abstract Display
Type: Poster
Title: Mobile monitoring of cognition in middle-aged and older adults with and without amnestic mild cognitive impairment: Implications for Alzheimer’s disease clinical trials.
Authors: Campbell LM, Delgadillo J, Paolillo EW, Sundermann E, Holden J, Schweitzer P, Swendsen J, Moore RC
Date: 07-13-2019
Abstract:Neuropsychological testing methods used in clinical trails are labor-intensive, expensive, and only represent a "snapshot" of cognitive functioning at one time. Natural diurnal variation in cognition may obscure our ability to detect change in cognitive functioning. We have developed mobile cognitive tests to assess contextual influences on cognitive performance and dynamics of cognitive ability over time. Here, we discuss the feasibility, acceptability, and validity of one test: the mobile color-word interference test (mCWIT), administered daily for 14 days, among older persons with and without amnestic mild cognitive impairment (aMCI) and co-occurring medical comorbidities (e.g., HIV).

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