| Publication Abstract Display | | Type: Published Abstract | | Title: Cognitive complaints neuropsychological ability, and depressive symptoms in HIV. | | Authors: Moore D, Gonzalez R, Heaton R, Rippeth J, Cherner M, Grant I, and the HNRC Group | | Year: 2001 | | Publication: Journal of the International Neuropsychological Society | | Volume: 7 Issue: 2 Pages: 149 | | Abstract:Recently published studies suggest that cognitive complaints in HIV-1 infection are related to both depressive symptoms and to a lesser degree neuropsychological (NP) ability. The objective of the current study was to test this cross-sectional finding in our sample and to examine the factors that lead to changes in cognitive complaints over time. Method: We examined 258 HIV+ individuals who completed a comprehensive NP battery, the Beck Depression Inventory (BDI), and the Patient's Assessment of Own Functioning Inventory (PAOFI). Ninety-one (35%) were classified as NP impaired based on blind clinical ratings of demographically corrected T scores. Eighty-two (32%) had an AIDS diagnosis. Results: Individuals with AIDS were similar with regard to NP status, average BDI score, and average number of cognitive complaints when compared to HIV1 individuals who did not have an AIDS diagnosis. As previous research has suggested, BDI scores were significant predictors of cognitive complaints. AIDS diagnosis and NP status were not significant predictors of cognitive complaints when depressive symptoms were included in the model. Furthermore, no specific NP abilities aided in the prediction of cognitive complaints after controlling for depression. To determine whether this pattern of results continued over time, we examined the change in depressive symptoms, NP status, and cognitive complaints from one testing to the next. Longitudinally, BDI continued to be the only significant predictor of cognitive complaints. Discussion: It appears that depressive symptoms are the best predictor of cognitive complaints cross-sectionally and longitudinally. |
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