| Publication Abstract Display | | Type: Published Manuscript | | Title: Peripheral inflammation and depressed mood independently predict neurocognitive worsening over 12 years. | | Authors: Ellis RJ, Heaton RK, Tang B, Collier AC, Marra CM, Gelman BB, Morgello S, Clifford DB, Sacktor N, Cookson D, Letendre S | | Year: 2022 | | Publication: Brain, Behavior, & Immunity - Health | | Volume: 21 Issue: Pages: 100437 | | Abstract:Neurocognitive (NC) impairment in people with HIV (PWH) is associated with important adverse outcomes, but no markers exist to predict long-term NC decline. We evaluated depressed mood and markers of persistent inflammation, oxidative stress and altered amyloid processing (all common in PWH) as predictors of NC worsening over 12 years. |
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