Publication Abstract Display | Type: Published Manuscript | Title: Use of neuroimaging to inform optimal neurocognitive criteria for detecting HIV-associated brain abnormalities. | Authors: Campbell LM, Fennema-Notestine C, Saloner R, Hussain M, Chen A, Franklin D, Umlauf A, Ellis RJ, Collier AC, Marra CM, Clifford DB, Gelman BB, Sacktor N, Morgello S, McCutchan JA, Letendre S, Grant I, Heaton RK | Year: 2020 | Publication: Journal of The International Neuropsychological Society | Volume: 26 Issue: 2 Pages: 147-162 | Abstract:Frascati international research criteria for HIV-associated neurocognitive disorders (HAND) are controversial; some investigators have argued that Frascati criteria are too liberal, resulting in a high false positive rate. Meyer et al. recommended more conservative revisions to HAND criteria, including exploring other commonly used methodologies for neurocognitive impairment (NCI) in HIV including the global deficit score (GDS). This study compares NCI classifications by Frascati, Meyer, and GDS methods, in relation to neuroimaging markers of brain integrity in HIV. |
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