| Publication Abstract Display | | Type: Published Abstract | | Title: ART resistance influences CSF HIV RNA levels and neuropsychological performance in HIV-infected individuals. | | Authors: Hightower G, Letendre S, Cherner M, Gibson S, Ellis R, Ignacio C, Heaton R, Grant I, Richman D, Smith D, and the HNRC Group | | Year: 2008 | | Publication: 15th Annual Conference on Retroviruses and Opportunistic Infections | | Volume: Session 20 Issue: Pages: 394 | | Abstract:"Background: ART can significantly lower viral replication in the central nervous system (CNS) and improve neuropsychological performance; however, this effect can vary significantly. The influence of ART resistance on viral dynamics in the CNS may in part explain this variability. Our objectives were to determine if there is an association between ART resistance and neuropsychological performance and if ART resistance changes the association between neuropsychological impairment and cerebrospinal fluid (CSF) HIV RNA levels. |
return to publications listing
|