Publication Abstract Display | Type: Poster | Title: Detectable CMV in PBMC is associated with slower HIV DNA decay during suppressive ART. | Authors: Gianella S, Anderson C, Var S, Oliveira M, Massanella M, Little S, Richman D, Strain M, Perez-Santiago J, Smith D | Date: 02-23-2015 | Abstract:Conclusions:
Detectable CMV DNA in PBMC was longitudinally
associated with higher HIV DNA levels, even among
individuals who started ART early during HIV infection,
suggesting that CMV replication may help maintain the
stability of the HIV DNA reservoir.
Future studies with anti-CMV therapeutics could help
determine underlying mechanisms and if causal
associations exist. |
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