Publication Abstract Display
Type: Poster
Title: Impact of advancing age on cognition in HIV+ persons on a first suppressive regimen.
Authors: Coban H, Robertson K, Smurzynski M, Krishnan S, Wu K, Bosch R, Collier A, Ellis R
Date: 02-13-2017
Abstract:Conclusions: In the context of long-term ART (2 or more years after starting initial treatment), older age was a significant risk factor for neurocognitive impairment Age-related neurocognitive impairment was seen despite continued virologic suppression in most and despite neurocognitive improvement (lower impairment rate at later follow-up visits) in the cohort as a whole. Potential causes of age-related neurocognitive impairment: ART-related adverse effects of common age-related comorbidities (diabetes, hypertension, hyperlipidemia) Greater CNS toxicities of ART in older versus younger participants.

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