| Publication Abstract Display | | Type: Published Manuscript | | Title: Molecular epidemiology of HIV-1 clades in Southern Brazil. | | Authors: Raboni SM, de Almeida SM, Rotta I, Lopes Ribeiro CE, Rosario D,
Vidal LR, Nogueira MB, Riedel M,
Winhescki M, Ferreira KA, Ellis R | | Year: 2010 | | Publication: Mem Inst Oswaldo Cruz | | Volume: 105 Issue: 8 Pages: 1044-1049 | | Abstract:Human immunodeficiency virus (HIV) clades B and C account for more than 60% of the HIV-1 infections worldwide.
In this paper, we describe the profiles of patients infected with subtypes of HIV-1 from the state of Paraná,
Southern Brazil, and correlate them with demographic and epidemiological findings. A retrospective analysis of
HIV cases reported from 1999-2007 was also performed. Data from 293 patients were reviewed and 245 were older
than 13 (58% female). The distribution of clades was as follows: B 140 (57%), C 67 (23%), F 24 (10%) and mosaic or
unique recombinant forms (URFs) 24 (10%). Of the 48 patients younger than 13 years of age (62.5% male), vertical
transmission occurred in 46 and the distribution of clades was as follows: B 14 (29%), C 24 (50%), F 7 (15%) and
URFs 6 (13%). There was no significant difference in mortality between HIV-1 subtypes. In both groups, patients
infected with clade C tended to have higher rates of injection drug use exposure risk. |
return to publications listing
|