Publication Abstract Display
Type: Published Manuscript
Title: Aging, prospective memory, and health-related quality of life in HIV infection.
Authors: Doyle K, Weber E, Atkinson JH, Grant I, Woods SP, and the HNRP Group
Year: 2012
Publication: AIDS And Behavior
Volume: 16 Issue: 8 Pages: 2309-2318
Abstract:HIV infection and older age are each independently associated with lower health-related quality of life (HRQoL) and deficits in prospective memory (PM), which is a distinct aspect of cognition involving the ability to "remember to remember" to do something at a future occasion. The present study investigated associations between PM and HRQoL in 72 older (≥50 years) and 41 younger (≤40 years) HIV-infected adults. Self-reported PM complaints predicted HRQoL across the entire sample, but there was a significant interaction between performance-based PM and age group on HRQoL, such that lower time-based PM was associated with lower HRQoL only in the younger cohort. Within the younger group, time-based and self-reported PM significantly predicted mental HRQoL independent of other risk factors (e.g. depression). These findings suggest that PM plays a unique role in HRQoL outcomes among younger persons living with HIV infection and support the examination of other age-related factors (e.g. effective use of compensatory strategies) that may regulate the adverse impact of PM on everyday functioning.

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