Publication Abstract Display
Type: Published Manuscript
Title: Human Immunodeficiency Virus-Type 1 (HIV-1) and the brain.
Authors: Grant I, Heaton RK
Contact: University of California, San Diego School of Medicine.
Year: 1990
Publication: Journal of Consulting and Clinical Psychology
Volume: 58 Issue: 1 Pages: 22-30
Abstract:nfection with human immunodeficiency virus Type-1 (HIV-1), the causative agent of AIDS, can be associated with central nervous system as well as immune system disease. Advanced AIDS can be complicated by a dementia. Short of frank dementia, many AIDS patients manifest neuropsychological (NP) impairment including disturbance in speeded information processing, abstraction, learning, and recall. Data conflict on whether medically asymptomatic HIV-1 carriers have subtle NP deficits. Variations in tests chosen, criterion specification, and sample selection may all be contributing to disparate results. Longitudinal research is needed, and this should examine representative samples of HIV-1 seropositive individuals for whom approximate date of seroconversion is known and in whom sources of comorbidity (e.g., drug abuse, concurrent infections, CNS injuries) can be specified.
Funding: NIMH:MH MH43298-02
Keywords: AIDS Dementia Complex, Acquired Immunodeficiency Syndrome, Brain, HIV-1, Humans, Incidence, Research Support, U.S. Gov''t, P.H.S., Time Factors

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