Publication Abstract Display
Type: Published Manuscript
Title: HIV protease inhibitor exposure predicts cerebral small vessel disease.
Authors: Soontornniyomkij V, Umlauf A, Chung SA, Cochran ML, Soontornniyomkij B, Gouaux B, Toperoff W, Moore DJ, Masliah E, Ellis RJ, Grant I, Achim CL
Year: 2014
Publication: AIDS (London, England)
Volume: 28 Issue: 9 Pages: 1297-1306
Abstract:HIV-associated neurocognitive disorders (HANDs) remain prevalent in patients who receive HAART and may be associated with cumulative exposure to antiretroviral medications and other factors. We proposed that chronic toxic effects of antiretroviral drugs could contribute to cerebral small vessel disease (CSVD), which might be one of the key underpinnings of HAND.

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