Publication Abstract Display
Type: Published Manuscript
Title: Cerebrospinal fluid (CSF) CD8+ T-Cells that express Interferon-Gamma contribute to HIV associated neurocognitive disorders (HAND).
Authors: Schrier RD, Hong S, Crescini M, Ellis R, Pérez-Santiago J, Spina C, Letendre S
Year: 2015
Publication: PloS One
Volume: 10 Issue: 2 Pages: e0116526
Abstract:HIV associated neurocognitive disorders (HAND) continue to affect cognition and everyday functioning despite anti-retroviral treatment (ART). Previous studies focused on mechanisms related to monocyte/macrophage mediated inflammation. However, in the ART era, there is increasing evidence for the involvement of CD8+ T-cells in CNS pathogenesis.

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