Publication Abstract Display | Type: Published Manuscript | Title: Physical activity is associated with better neurocognitive and everyday functioning among older adults with HIV disease. | Authors: Fazeli P, Marquine MJ, Dufour C, Henry BL, Montoya J, Gouaux B, Moore RC, Letendre SL, Woods SP, Grant I, Jeste DV, Moore DJ | Year: 2015 | Publication: AIDS And Behavior | Volume: 19 Issue: 8 Pages: 1470-1477 | Abstract:We examined the association between physical activity (PA), neurocognitive impairment (NCI), and instrumental activities of daily living (IADLs) among older HIV+ persons. One hundred older HIV+ adults completed the International Physical Activity Questionnaire, a neurocognitive battery, and IADL scale. Higher levels of moderate PA were associated with lower odds of NCI (p = 0.01), even when covariates were modeled. The association between moderate PA and NCI was driven by executive function (p = 0.04). Higher levels of moderate PA were also associated with lower odds of IADL Dependence (p = 0.03), although this fell to a trend (p = 0.08) when including covariates. Follow-up analysis showed those with both NCI and IADL Dependence had lower moderate PA than those with neither (p = 0.03). While these cross-sectional findings suggest PA is associated with better neurocognitive and everyday functioning in older HIV+ adults, longitudinal studies utilizing objective PA methods are needed to evaluate directionality and mechanisms. |
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