Publication Abstract Display
Type: Published Manuscript
Title: Amphetamine increases activity but not exploration in humans and mice.
Authors: Minassian A, Young JW, Cope ZA, Henry BL, Geyer MA, Perry W
Year: 2016
Publication: Psychopharmacology
Volume: 233 Issue: 2 Pages: 225-233
Abstract:Cross-species quantification of physiological behavior enables a better understanding of the biological systems underlying neuropsychiatric diseases such as bipolar disorder (BD). Cardinal symptoms of manic BD include increased motor activity and goal-directed behavior, thought to be related to increased catecholamine activity, potentially selective to dopamine homeostatic dysregulation.

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