Publication Abstract Display | Type: Published Manuscript | Title: Distinct effects of SSRIs and SNRIs on soluble biomarkers in blood and cerebrospinal fluid of people with HIV. | Authors: Trunfio M, Tang B, Iudicello JE, Ma Q, Franklin DR, Cookson D, Riggs PK, Cherner M, Moore DJ, Heaton RK, Letendre SL, Ellis RJ | Year: 2023 | Publication: The Journal of Infectious Diseases | Volume: Epub Dec 6 Issue: Pages: | Abstract:Persistent inflammation affects people with HIV (PWH) despite antiretroviral therapy (ART). Selective serotonin and serotonin-norepinephrine reuptake inhibitors (SSRIs, SNRIs), HMG-CoA reductase-inhibitors (statins), and angiotensin-converting enzyme inhibitors (ACEIs) have immuno-modulant properties. We evaluated the potential impact of these drugs on inflammation and neurodegeneration in PWH. |
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