Publications | Abstracts

Cahill C, Alayoubi M, Rodrigues A, Wu C, Whitehouse E, Nguyen J, Cooper ZD, O'Neill PR.  (2025). Elucidating interplay between myrcene and cannabinoid receptor 1 receptors to produce antinociception in mouse models of neuropathic pain. Pain, Epub Mar 18. PMID: 40096521   Corroon J, Bradley R, Allison MA, Grant I.  (2024). Blood pressure and hypertension in older adults who regularly smoke cannabis: Findings from the Multi-Ethnic Study of Atherosclerosis (MESA). Frontiers in Cardiovascular Medicine, 11, 1432923. PMID: 39539498  PMCID: 11557345   Kulik MC, Lee YO, Butsic V, Cermak TL, Cooper ZD, Corva D, Marcotte TD, Uskup DK, McKnight TR, Balla A.  (2024). California Cannabis Research Briefing, April 2023: Meeting Summary. Cannabis and Cannabinoid Research, Epub May 7. PMID: 38717853   Beletsky A, Liu C, Lochte B, Samuel N, Grant I.  (2024). Cannabis and anxiety: A critical review. Med Cannabis Cannabinoids, 7(1), 19-30. PMID: 38406383  PMCID: 10890807   Avalos B, Kulbe JR, Ford MK, Laird AE, Walter K, Mante M, Florio JB, Boustani A, Chaillon A, Schlachetzki JCM, Sundermann EE, Volsky DJ, Rissman RA, Ellis RJ, Letendre SL, Iudicello J, Fields JA.  (2024). Cannabis use and cannabidiol modulate HIV-Induced alterations in TREM2 expression: Implications for age-related neuropathogenesis. Viruses, 16(10), 1509. PMID: 39459844  PMCID: 11512329   Wilson JN, Mendez DA, Dhoro F, Shevchenko N, Mescal M, Lund K, Fitzgerald R, DiPatrizio NV, Ortiz RM.  (2024). Pseudocannabinoid H4CBD improves glucose response during advanced metabolic syndrome in OLETF rats independent of increase in insulin signaling proteins. American Journal of Physiol Intgr Comp Physiol, 326(2), R100-R109. PMCID: 37899754   Corroon J, Bradley R, Grant I, Daniels MR, Denenberg J, Bancks MP, Allison MA.  (2024). Regular cannabis smoking and carotid artery calcification in the Multi-Ethnic Study of Atherosclerosis (MESA). Vascular Medicine, 29(6), 621-631. PMID: 39439386  PMCID: 11590377   Ayoub SM, Holloway BM, Miranda AH, Roberts BZ, Young JW, Minassian A, Ellis RJ.  (2024). The impact of cannabis use on cognition in people with HIV: Evidence of function-dependent effects and mechanisms from clinical and preclinical studies. Current HIV/AIDS Reports, 21(3), 87-115. PMID: 38602558  PMCID: 11129923   Schuster NM, Wallace MS, Marcotte TD, Buse DC, Lee E, Liu L, Sexton M.  (2024). Vaporized cannabis versus placebo for acute migraine: A randomized controlled trial. MedRxiv, Epub Feb 18. PMID: 38405890  PMCID: 10889030   Watson CW-M, Sundermann E, Helm J, Paolillo EW, Hong S, Ellis RJ, Letendre S, Marcotte TD, Heaton RK, Morgan EE, Grant I.  (2023). A longitudinal study of cannabis use and risk for cognitive and functional decline among older adults with HIV. AIDS and Behavior, 27(10), 3401-3413. PMID: 37155086  PMCID: 10766343   Corroon J, Grant I, Allison MA, Bradley R.  (2023). Associations Between Monthly Cannabis Use and Myocardial Infarction in Middle-Aged Adults: NHANES 2009 to 2018. American Journal of Cardiology, 204, 226-233. PMID: 37556891  PMCID: 10998689   Rogers JM, Grant I, Marcondes MCG, Morgan EE, Cherner M, Ellis RJ, Letendre SL, Heaton RK, Iudicello JE.  (2023). Cannabis use may attenuate neurocognitive performance deficits resulting from methamphetamine use disorder. Journal of the International Neuropsychological Society, 30(1), 84-93. PMID: 37553288  PMCID: 10841263   Fitzgerald RL, Umlauf A, Hubbard JA, Hoffman MA, Sobolesky PM, Ellis SE, Grelotti DJ, Suhandynata RT, Huestis MA, Grant I, Marcotte TD.  (2023). Driving under the influence of cannabis: Impact of combining toxicology testing with field sobriety tests. Clinical Chemistry, 59(7), 724-733. PMID: 37228223  PMCID: 10320013   Marcotte TD, Umlauf A, Grelotti DJ, Sones EG, Mastropietro KF, Suhandynata RT, Huestis MA, Grant I, Fitzgerald RL.  (2023). Evaluation of field sobriety tests for identifying drivers under the influence of cannabis: A randomized clinical trial. JAMA Psychiatry, 80(9), 914-923. PMID: 37531115  PMCID: 10398547   Leas EC, Harati RM, Satybaldiyeva N, Morales NE, Huffaker SL, Mejorado T, Grant I.  (2023). Self-reported adverse events associated with ∆8-tetrahydrocannabinol (Delta-8-THC) use. Journal of Cannabis Research, 5(1), 15. PMID: 37217977  PMCID: 10204335   Rogers JM, Iudicello JE, Marcondes MCG, Morgan EE, Cherner M, Ellis RJ, Letendre SL, Heaton RK, Grant I.  (2023). The combined effects of cannabis, methamphetamine, and HIV on neurocognition. Viruses, 15(3), 674. PMID: 36992383  PMCID: 10058939   Corroon J, Grant I, Bradley R, Allison MA.  (2023). Trends in cannabis use, blood pressure and hypertension in middle-aged adults: Findings from NHANES, 2009-2018. American Journal of Hypertension, 36(12), 651-659. PMID: 37479221  PMCID: 10647009   Liyanage M, Nikanjam M, Capparelli EV, Suhandynata RT, Fitzgerald RL, Marcotte TD, Grant I, Momper JD.  (2023). Variable Delta-9-Tetrahydrocannabinol Pharmacokinetics And Pharmacodynamics After Cannabis Smoking in Regular Users. Therapeutic Drug Monitoring, 45(5), 689-696. PMID: 37199428   Smith RC, Sershen H, Janowsky DS, Lajtha A, Grieco M, Gangoiti JA, Gertsman I, Johnson WS, Marcotte TD, Davis JM.  (2022). Changes in expression of DNA-methyltransferase and cannabinoid receptor MRNAs in blood lymphocytes after acute cannabis smoking. Frontiers in Psychiatry, 13, 887700. PMID: 35859599  PMCID: PMC9290435   Wiley MB, DiPatrizio NV.  (2022). Diet-induced gut barrier dysfunction is exacerbated in mice lacking cannabinoid 1 receptors in the intestinal epithelium. International Journal of Molecular Science, 23(18), 10549. PMID: 36142461  PMCID: PMC9504303   Marcotte TD, Umlauf A, Grelotti DJ, Sones EG, Sobolesky PM, Smith BE, Hoffman MA, Hubbard JA, Severson J, Huestis MA, Grant I, Fitzgerald RL.  (2022). Driving performance and cannabis users' perception of safety. JAMA Psychiatry, 79(3), 201-209. PMID: 35080588  PMCID: PMC8792796   Basova LV, Lukkes SE, Milner R, Ellis RJ, Cherner M, Iudicello J, Marcondes MCG.  (2022). Polygenic networks in peripheral leukocytes indicate patterns associated with HIV infection and context-dependent effects of cannabis use. Brain, Behavior, & Immunity - Health, 20, 100414. PMID: 35128491  PMCID: PMC8808072   Mosaed S, Smith AK, Liu JHK, Minckler DS, Fitzgerald RL, Grelotti D, Sones E, Weinreb RN, Marcotte TD.  (2022). The relationship between plasma tetrahydrocannabinol levels and intraocular pressure in healthy adult subjects. Frontiers in Medicine, 8, 736792. PMID: 35111768  PMCID: PMC8801518   Swinton MK, Sundermann EE, Pedersen L, Nguyen JD, Grelotti DJ, Taffe MA, Iudicello JE, Fields JA.  (2021). Alterations in brain cannabinoid receptor levels are associated with HIV-associated neurocognitive disorders in the ART era: Implications for therapeutic strategies targeting the endocannabinoid system. Viruses, 13(9), 1742. PMID: 34578323  PMCID: PMC8473156   Ellis RJ, Peterson S, Cherner M, Morgan E, Schrier R, Tang B, Hoenigl M, Letendre S, Iudicello J.  (2021). Beneficial effects of cannabis on blood brain barrier function in HIV. Clinical Infectious Diseases, 73(1), 124-129. PMID: 32296832   Hubbard JA, Hoffman MA, Ellis SE, Sobolesky PM, SMith BE, Suhandynata RT, Sones EG, Sanford SK, Umlauf A, Huestis MA, Grelotti DG, Grant I, Marcotte TD, Fitzgerald RL.  (2021). Biomarkers of recent cannabis use in blood, oral fluid and breath. Journal of Analytical Toxicology, 45(8), 820-828. PMID: 34185831   Hoffman MA, Hubbard JA, Sobolesky PM, Smith BE, Suhandynata RT, Sanford S, Sones E, Ellis S, Umlauf A, Huestis MA, Grelotti DJ, Grant I, Marcotte TD, Fitzgerald RL.  (2021). Blood and oral fluid cannabinoid profiles of frequent and occasional cannabis smokers. Journal of Analytical Toxicology, 45(8), 851-862. PMID: 34173005   Smith LC, Tieu L, Suhandynata RT, Boomhower B, Hoffman M, Sepulveda Y, Carrett LLG, Momper JD, Fitzgerald RL, Hanham K, Dowling J, Kallupi M, George O.  (2021). Cannabidiol reduces withdrawal symptoms in nicotine-dependent rats. Psychopharmacology, 238(8), 2201-2211. PMID: 33909102  PMCID: PMC8295227   Ellis RJ, Wilson N, Peterson S.  (2021). Cannabis and inflammation in HIV: A review of human and animal studies. Viruses, 13(8), 1521. PMID: 34452386  PMCID: PMC8402692   Wilson NL, Peterson SN, Ellis RJ.  (2021). Cannabis and the gut-brain axis communication in HIV infection. Cannabis And Cannabinoid Research, 6(2), 92-104. PMID: 33912676  PMCID: PMC8064954   Kiendrebeogo P, Grelotti D, Cherner M, Moore RC, Tang B, Ellis RJ.  (2021). Cannabis use is not associated with increased balance disturbances in HIV-infected individuals. Journal of Cannabis Research, 3(1), 3. PMID: 33536072  PMCID: PMC7860021   Watson CW, Campbell LM, Sun-Suslow N, Hong S, Umlauf A, Ellis RJ, Iudicello JE, Letendre S, Marcotte TD, Heaton RK, Morgan EE, Grant I.  (2021). Daily cannabis use is associated with lower CNS inflammation in people with HIV. Journal of the International Neuropsychological Society, 27(6), 661-672. PMID: 34261550  PMCID: PMC8288448   Roberts BZ, Minassian A, Halberstadt AL, He YV, Chatha M, Geyer MA, Grant I, Young JW.  (2021). HIV transgenic rats demonstrate impaired sensorimotor gating, but are insensitive to cannabinoid (delta-9-tetrahydrocannabinol)-induced deficits. The International Journal of Neuropsychopharmacology, 24(11), 894-906. PMID: 34338765  PMCID: PMC8598295   Pocuca N, Walter TJ Minassian A Young JW, Geyer MA, Perry W.  (2021). The effects of cannabis use on cognitive function in healthy aging: A systematic scoping review. Archives of Clinical Neuropsychology, 36(5), 673-685. PMID: 33159510  PMCID: PMC8296849   Walter TJ, Pocuca N, Young JW, Geyer MA, Minassian A, Perry W.  (2021). The relationship between cannabis use and cognition in people with bipolar disorder: A systematic scoping review. Psychiatry Research, 297, 113695. PMID: 33545431  PMCID: PMC7914198   Wallace MS, Marcotte TD, Atkinson JH, Padovano HT, Bonn-Miller M.  (2020). A secondary analysis from a randomized trial on the effect of plasma tetrahydrocannabinol levels on pain reduction in painful diabetic peripheral neuropathy. The Journal of Pain : Official Journal of The American Pain Society, 21(11-12), 1175-1186. PMID: 32565122   Watson CW, Paolillo EW, Morgan EE, Umlauf A, Sundermann EE, Ellis RJ, Letendre S, Marcotte TD, Heaton RK, Grant I.  (2020). Cannabis exposure is associated with a lower likelihood of neurocognitive impairment in people living with HIV. Journal of Acquired Immune Deficiency Syndromes, 83(1), 56-64. PMID: 31809361  PMCID: PMC6901104   Campbell LM, Tang B, Watson C WM, Higgins M, Cherner M, Henry BL, Moore RC.  (2020). Cannabis use is associated with greater total sleep time in middle-aged and older adults with and without HIV: A preliminary report utilizing digital health technologies. Cannabis (Research Society On Marijuana), 3(2), 180-189. PMID: 32905460   Chaillon A, Nakazawa M, Anderson C, Christensen-Quick A, Ellis RJ, Franklin D, Morris SR, Gianella S.  (2020). Effect of cannabis use on HIV DNA during suppressive ART. Clinical Infectious Diseases, 70(1), 140-143. PMID: 31074488  PMCID: PMC6912153   Saloner R, Fields JA, Marcondes MCG, Iudicello JE, von Kanel S, Cherner M, Letendre SL, Kaul M, Grant I, and the TMARC Group.  (2020). Methamphetamine and cannabis: A tale of two drugs and their effects on HIV, brain, and behavior. Journal of Neuroimmune Pharmacology, 15(4), 743-764. PMID: 32929575  PMCID: PMC7719083   Ellis RJ, Peterson SN, Li Y, Schrier R, Iudicello J, Letendre S, Morgan E, Tang B, Grant I, Cherner M.  (2020). Recent cannabis use in HIV is associated with reduced inflammatory markers in CSF and blood. Neurology, Neuroimmunology & Neuroinflammation, 7(5), e809. PMID: 32554630  PMCID: PMC7309527   Mosaed S, Liu JHK, Minckler DS, Fitzgerald RL, Grelotti D, Sones E, Shiels CR, Weinreb RN, Marcotte TD.  (2020). The effect of inhaled cannabis on intraocular pressure in healthy adult subjects. TouchReviews in Ophthalmology, 15(1), 33-37.  Hubbard JA, Smith BE, Sobolesky PM, Kim S, Hoffman MA, Stone J, Huestis MA, Grelotti DJ, Grant I, Marcotte T, Fitzgerald RL.  (2020). Validation of a liquid chromatography tandem mass spectrometry (LC-MS/MS) method to detect cannabinoids in whole blood and breath. Clinical Chemistry And Laboratory Medicine, 58(5), 673-681. PMID: 31527291   Tyree GA, Sarkar R Bellows BK, Ellis RJ, Atkinson JH, Marcotte TD, Wallace MS, Grant I, Shi Y, Murphy JD, Grelotti DJ.  (2019). A cost-effectiveness model for adjunctive smoked cannabis in the treatment of chronic neuropathic pain. Cannabis And Cannabinoid Research, 4(1), 62-72. PMID: 30944870  PMCID: PMC6446169   Piomelli D, Solomon R, Abrams D, Balla A, Grant I, Marcotte T, Yoder J.  (2019). Regulatory barriers to research on cannabis and cannabinoids: a proposed path forward. Cannabis and Cannabinoid Research. Cannabis and Cannabinoid Research, 4(1), 21-32. PMID: 35236017  PMCID: PMC8884193   Sobolesky PM, Smith BE, Hubbard JA, Stone J, Marcotte TD, Grelotti DJ, Grant I, Fitzgerald RL.  (2019). Validation of a liquid chromatography-tandem mass spectrometry method for analyzing cannabinoids in oral fluid. Clinica Chimica Acta; International Journal of Clinical Chemistry, 491, 30-38. PMID: 30615854   Liang D, Bao Y, Wallace M, Grant I, Shi Y.  (2018). Medical cannabis legalization and opioid prescriptions: Evidence on US Medicaid enrollees during 1993-2014. Addiction (Abingdon, England), 113(11), 2060-2070. PMID: 29989239  PMCID: PMC6190827   Shi Y, Liang D, Bao Y, An R, Wallace MS, Grant I.  (2018). Recreational marijuana legalization and prescription opioids received by Medicaid enrollees. Drug and Alcohol Dependence, 194, 13-19. PMID: 30390550  PMCID: PMC6318121   Paolillo EW, Obermeit LC, Tang B, Depp CA, Vaida F, Moore DJ, Moore RC.  (2018). Smartphone-based ecological momentary assessment (EMA) of alcohol and cannabis use in older adults with and without HIV infection. Addictive Behaviors, 83, 102-108. PMID: 29126667  PMCID: PMC5920804   Piomelli D, Cooper Z, Abrams D, Grant I, Patel S.  (2017). A guide to the National Academy of Science report on cannabis: An exclusive discussion with panel members. Cannabis And Cannabinoid Research, 2(1), 155-159. PMID: 28861515  PMCID: PMC5569624   Lochte BC, Beletsky A, Samuel NK, Grant I.  (2017). The use of cannabis for headache disorders. Cannabis and Cannabinoid Research, 2(1), 61-71. PMID: 288615  PMCID: PMC5436634   Wilsey BL, Deutsch R, Samara E, Marcotte TD, Barnes AJ, Huestis MA, Le D.  (2016). A preliminary evaluation of the relationship of cannabinoid blood concentrations with the analgesic response to vaporized cannabis. Journal of Pain Research, 9, 587-98. PMID: 27621666  PMCID: PMC5012851   Wilsey B, Marcotte TD, Deutsch R, Zhao H, Prasad H, Phan A.  (2016). An exploratory human laboratory experiment evaluating vaporized cannabis in the treatment of neuropathic pain from spinal cord injury and disease. The Journal of Pain : Official Journal of The American Pain Society, 17(9), 982-1000. PMID: 27286745   Wallace MS, Marcotte TD, Umlauf A, Gouaux B, Atkinson JH.  (2015). Efficacy of inhaled cannabis on painful diabetic neuropathy. The Journal of Pain : Official Journal of The American Pain Society, 16(7), 616-627. PMID: 25843054  PMCID: NA   Andreae MH, Carter GM, Shaparin N, Suslov K, Ellis RJ, Ware MA, Abrams DI, Prasad H, Wilsey B, Indyk D, Johnson M, Sacks HS.  (2015). Inhaled cannabis for chronic neuropathic pain: An individual patient data meta-analysis. The Journal of Pain, 16(12), 1221-1232. PMID: 26362106  PMCID: PMC4666747   Grant I.  (2015). Medical Use of Cannabinoids--Reply. Comment on Cannabinoids for Medical Use: A Systematic Review and Meta-analysis. JAMA: The Journal of the American Medical Association, 314(16), 1750-1751. PMID: 26505602   Wilsey B, Atkinson JH, Marcotte TD, Grant I.  (2015). The Medicinal Cannabis Treatment Agreement: Providing information to chronic pain patients via a written document. The Clinical Journal of Pain, 31(12), 1087-1096. PMID: 25370134  PMCID: PMC4417655     Cattie J, Grant I.  (2014). Cannabis. In DN Allen and SP Woods (Eds.), Neuropsychological Aspects of Substance Use Disorders. , (pp. 134-156). New York: Oxford University Press. Wilsey B, Marcotte T, Deutsch R, Gouaux B, Sakai S, Donaghe H.  (2013). Low-Dose Vaporized Cannabis Significantly Improves Neuropathic Pain. Journal of Pain, 14(2), 136-148. PMID: 23237736  PMCID: PMC3566631   Grant I.  (2013). Medicinal cannabis and painful sensory neuropathy. The Virtual Mentor, 15(5), 466-9. PMID: 23680571   Grant I, Atkinson JH, Gouaux B, Wilsey B.  (2012). Medical marijuana: Clearing away the smoke. The Open Neurology Journal, 6, 18-25. PMID: 22629287  PMCID: 3358713   Grant I, Atkinson JH, Gouaux B.  (2012). Research on medical marijuana. The American Journal of Psychiatry, 169(10), 1119-20. PMID: 23032393   Corey-Bloom J, Wolfson T, Gamst A, Jin S, Marcotte TD, Bentley H, Gouaux B.  (2012). Smoked cannabis for spasticity in Multiple Sclerosis: A randomized, placebo-controlled trial. Canadian Medical Association Journal, 184(10), 1143-50. PMID: 22586334  PMCID: PMC3394820   Riggs PK, Vaida F, Rossi SS, Sorkin LS, Gouaux B, Grant I, Ellis RJ.  (2011). A pilot study of the effects of cannabis on appetite hormones in HIV-infected adult men. Brain Research, 1431, 46-52. PMID: 22133305   Ellis RJ, Toperoff W, Vaida F, van den Brande G, Gonzales J, Gouaux B, Bentley H, Atkinson JH.  (2009). Smoked medicinal cannabis for neuropathic pain in HIV: a randomized, crossover clinical trial. Neuropsychopharmacology : Official Publication of The American College of Neuropsychopharmacology, 34(3), 672-80. PMID: 18688212  PMCID: PMC3066045   Wilsey B, Marcotte T, Tsodikov A, Millman J, Bentley H, Gouaux B, Fishman S.  (2008). A randomized, placebo-controlled, crossover trial of cannabis cigarettes in neuropathic pain. The Journal of Pain : Official Journal of The American Pain Society, 9(6), 506-521. PMID: 18403272   Abrams DI, Jay CA, Shade SB, Vizoso H, Reda H, Press S, Kelly ME, Rowbotham MC, Petersen KL.  (2007). Cannabis in painful HIV-associated sensory neuropathy: a randomized placebo-controlled trial. Neurology, 68(7), 515-521. PMID: 17296917   Wallace M, Schulteis G, Atkinson JH, Wolfson T, Lazzaretto D, Bentley H, Gouaux B, Abramson I.  (2007). Dose-dependent effects of smoked cannabis on capsaicin-induced pain and hyperalgesia in healthy volunteers. Anesthesiology, 107(5), 785-96. PMID: 18073554     Gonzalez R, Martin EM, Grant I.  (2007). Marijuana. A Kalechsten & WG van Gorp (Eds.), Neuropsychology and Substance Use. State-of-the-Art and Future Directions. , (pp. 139-170). Taylor & Francis Group. Abrams DI, Vizoso HP, Shade SB, Jay C, Kelly ME, and Benowitz NL.  (2007). Vaporization as a Smokeless Cannabis Delivery System: A Pilot Study. Clinical Pharmacology and Therapeutics, 82(5), 572-578. PMID: 17429350   Rossi S, Yaksh T, Bentley H, van den Brande G, Grant I, Ellis R.  (2006). Characterization of interference with 6 commercial Delta9-tetrahydrocannabinol immunoassays by Efavirenz (glucuronide) in urine. Clinical Chemistry, 52, 896-7. PMID: 16638958   Grant I, Cahn BR.  (2005). Cannabis and endocannabinoid modulators: therapeutic promises and challenges. Clinical Neuroscience Research, 5(2-4), 185-199. PMID: 18806886  PMCID: PMC2544377   Papanastassiou AM, Fields HL, Meng ID.  (2004). Local application of the cannabinoid receptor agonist, WIN 55,212-2, to spinal trigeminal nucleus caudalis differentially affects nociceptive and non-nociceptive neurons. Pain, 107(3), 267-275. PMID: 14736589   Gonzalez R, Rippeth JD, Carey CL, Heaton RK, Moore DJ, Schweinsburg BC, Cherner M, Grant I.  (2004). Neurocognitive performance of methamphetamine users discordant for history of marijuana exposure. Drug and Alcohol Dependence, 76(2), 181-90. PMID: 15488342   Prentiss D, Power R, Balmas G, Tzuang G, Israelski DM.  (2004). Patterns of marijuana use among patients with HIV/AIDS followed in a public health care setting. Journal of Acquired Immune Deficiency Syndromes, 35(1), 38-45. PMID: 14707790   Grant I, Gonzalez R, Carey CL, Natarajan L, Wolfson T.  (2003). Non-acute (residual) neurocognitive effects of cannabis use: a meta-analytic study. Journal of the International Neuropsychological Society, 9(5), 679-89. PMID: 12901774   Gonzalez R, Carey C, Grant I.  (2002). Nonacute (residual) neuropsychological effects of cannabis use: a qualitative analysis and systematic review. Journal of Clinical Pharmacology, 42(11), 48S-57S. PMID: 12412836   Grant I, Rochford J, Fleming T, Stunkard A.  (1973). A neuropsychological assessment of the effects of moderate marijuana use. Journal of Nervous and Mental Disease, 156, 278-280. PMID: 4708887